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Open Heart Surgery clinical trials

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NCT ID: NCT05222256 Not yet recruiting - Open Heart Surgery Clinical Trials

Comparison Between Levosimendan and Adrenaline in CABG Patients

Start date: March 2022
Phase: N/A
Study type: Interventional

The aim of this study is to compare between levosimendan and adrenaline in patients with pre-existing impaired systolic function (EF 30-40%), undergoing elective on-pump CABG, as regards hemodynamics and echocardiographic parameters.

NCT ID: NCT05149235 Completed - Open Heart Surgery Clinical Trials

Gaming Technology and Cardiac Rehabilitation

Start date: March 10, 2022
Phase: N/A
Study type: Interventional

Moderate to vigorous physical activity has been shown to be associated with autonomic regulation of the heart measured with heart rate variability. Cardiac autonomic modulation can be evaluated by heart rate variability. Activity promoting games can be an effective tool to aid rehabilitation in clinical settings. Combining gaming with the ergo-cycle can facilitate improving patients' activity time spent on the cycle.

NCT ID: NCT05063370 Active, not recruiting - Right Heart Failure Clinical Trials

Levosimendan in Patients With Impaired Right Ventricular Function Undergoing Cardiac Surgery

Start date: August 18, 2021
Phase: Phase 2
Study type: Interventional

Perioperative right ventricular (RV) function is an important determinant of postoperative outcomes after cardiac surgery. Perioperative RV dysfunction increases the need for perioperative inotropic support, prolongs intensive care unit stay and increases in-hospital mortality, in this study, we aim to investigate the effect of the preoperative administration of levosimendan on the outcome of patients with compromised right ventricular function undergoing cardiac surgery

NCT ID: NCT04670367 Recruiting - Open Heart Surgery Clinical Trials

The Effects of Baduanjin Exercise on Meridian Energy and Heart Rate Variability in Patients Undergoing Cardiac Sugery

Start date: November 26, 2020
Phase: N/A
Study type: Interventional

Cardiac rehabilitation (CR) consists of supervised exercise training in conjunction with other secondary prevention interventions. However, CR is not widely used because of distance, financial resources, work and other time constraints, gender, age, social support, illness perceptions, and psychiatric problems. Baduanjin is a type of movement-based mind-body intervention. It is a form of traditional practice designed to promote physical and psychological health, manage symptoms, and relieve stress during illness. Patients with heart disease have frequently used it. The impacts of a Baduanjin exercise-based cardiac rehabilitation program for patients recovering from CAD under coronary artery bypass graft (CABG) or valve replacement on Meridian Energy Analysis Device (MEAD100, Med- Pex Enterprises, Taichung, Taiwan) and heart rate variability (HRV) has yet to be assessed. This trial evaluates whether the Baduanjin exercise would provide effective meridian energy and HRV in patients following CABG.

NCT ID: NCT04506762 Terminated - Open Heart Surgery Clinical Trials

Benefit of Peri-operative Bilateral ESP Catheters for Enhanced Recovery for Cardiac Surgery (ERCS)

ESP_ERCS
Start date: November 1, 2020
Phase: N/A
Study type: Interventional

To demonstrate if the addition of peri-operative regional analgesia by Bilateral ESP catheters improves the enhanced recovery program after open heart surgeries for the duration of hospitalisation, quality of analgesia, Consumption of peri-operative opioids, quality of recovery and quality of life. Patients will be randomly divided in 2 groups Group 1 With the actual standards of care for enhanced recovery after cardiac surgery including opioid sparing peri operative analgesia Group 2 With the actual standards of care for enhanced recovery after cardiac surgery replacing the opioid analgesia by a peri operative analgesia by bilateral ESP catheters

NCT ID: NCT04486690 Completed - Open Heart Surgery Clinical Trials

Neuroprotection During Open Heart Surgery

Start date: July 1, 2016
Phase: Phase 3
Study type: Interventional

Millions of individuals with coronary artery, or valvular heart disease have been given a new chance at life by heart surgery, but the potential for neurological injury is a great risk .Neural complications - including neurocognitive dysfunction and ischemic complications are complications of cardiac surgery that can restrict the improved quality of life. Propofol is one of the most popular agents used for induction of anesthesia. propofol reduces cerebral blood flow but maintains coupling with cerebral metabolic rate for oxygen and decreases intracranial pressure, allowing optimal intraoperative conditions. Ketamine is a non-competitive antagonist of NMDA receptors that has well documented neuroprotective effects against ischemic brain injury and glutamate-induced brain injury. ketamine has neuroprotective effects against oxygen-glucose deprivation injury

NCT ID: NCT04213040 Completed - Clinical trials for Postoperative Complications

Procalcitonin and Postoperative Outcome After Open-heart Surgery

Start date: January 1, 2013
Phase:
Study type: Observational [Patient Registry]

The aim of this study was to investigate the impact of serum values of procalcitonin (PCT), C-reactive protein (CRP) and lactate to predict postoperative complications in the early postoperative period after open-heart surgery with cardiopulmonary bypass (CPB).

NCT ID: NCT03955536 Active, not recruiting - Open Heart Surgery Clinical Trials

Comparison of the Effects of Different Physiotherapy and Rehabilitation Methods on Open Heart Surgery

Start date: February 1, 2019
Phase: N/A
Study type: Interventional

The aim of this study is to compare the effects of different physiotherapy and rehabilitation methods in hospitalization after Open Heart Surgery (OHS). In this context, it is planned that patients undergoing OHS surgery will be randomly divided into 3 groups. 1. Group routine cardiac rehabilitation program (RCRP) 2. Group RCRP and inspiratory muscle training 3. Group RCRP and virtual reality application Treatment of patients will be administered twice daily during their stay in the hospital. The patients will be evaluated by clinical measurements and scales based on patient notification and before and after the treatment and their effectiveness and superiority over each other will be determined.

NCT ID: NCT03806413 Not yet recruiting - Delirium Clinical Trials

Post-surgical Delirium in Patients Undergoing Open Heart Surgery.

Start date: October 1, 2024
Phase:
Study type: Observational [Patient Registry]

Post-surgical delirium in patients undergoing open heart surgery. Introduction Delirium occurs after open heart surgery may reach about 1/3 of the patients.(1) Aim The aim of this study is to determine the incidence of delirium after open heart surgery and the associated risk factors in Alexandria University hospital. Patients and Methods The study will be done on patients undergoing open heart surgery in Alexandria University hospitals from January 5th 2019 till January 4th 2020. The 6-item Cognitive Impairment Test (6CIT) and SPMSQ questionnaire will be used. SPMSQ will be done preoperative and daily for 3 days postoperative, at day 7. Phone call for SPMSQ will be done 3, 6 9 and 12 months after surgery.

NCT ID: NCT03799965 Recruiting - Clinical trials for Enhanced Recovery After Surgery

The Effect of Advanced Improvement Program (ERAS) on Postoperative Outcomes in Patients Undergoing Open Heart Surgery

Start date: December 1, 2017
Phase: N/A
Study type: Interventional

Investigation of the effect of Enhanced Recovery After Surgery (ERAS) program on postoperative results of patients operated for open heart surgery.