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Safety and Tolerability of a Prostaglandin Ocular Implant for Treatment of Open Angle Glaucoma

Open-angle Glaucoma Clinical Trial

Official title:
An Open-label Phase I Study to Evaluate the Safety, Tolerability and Biodegradation Period of PolyActiva PA5108 Ocular Implant When Administered Intracamerally to the Anterior Chamber of the Eye

Clinical Trial Summary

A single centre, open label, study to assess the safety, tolerability and biodegradation of PA5108 ocular implant in adults who have Open Angle Glaucoma (Primary or Secondary).

Clinical Trial Description

Participants who are currently managing their Open Angle Glaucoma with combination drop therapy will be recruited. Drop therapy will cease in the treatment eye and continue in the contralateral eye. The treated eye will receive via injection, a single PA5108 ocular implant. Participants will be monitored for safety and tolerability of the ocular implant until it completely biodegrades. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT03604328
Study type Interventional
Source PolyActiva Pty Ltd
Contact
Status Completed
Phase Phase 1
Start date July 24, 2018
Completion date June 15, 2020
View Details
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