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NCT00705770 Clinical Trial

A Multi-Dose Study With a Treatment for Open-Angle Glaucoma

Open-Angle Glaucoma Clinical Trial

Clinical Trial Details — Status: Withdrawn

Administrative data
NCT number NCT00705770
Other study ID # C-07-58
Secondary ID
Status Withdrawn
Phase Phase 2/Phase 3
First received June 24, 2008
Last updated May 29, 2012
Start date May 2008
Est. completion date July 2008

Study information
Verified date July 2008
Source Alcon Research
Contact n/a
Is FDA regulated No
Health authority United States: Food and Drug Administration
Study type Interventional

Clinical Trial Summary

The purpose of this study is to determine whether Anecortave Acetate is effective for lowering intraocular pressure caused by open-angle glaucoma.

Recruitment information / eligibility
Status Withdrawn
Enrollment 0
Est. completion date July 2008
Est. primary completion date July 2008
Accepts healthy volunteers No
Gender Both
Age group 18 Years and older
Eligibility Inclusion Criteria:

- Patients at least 18 years old with a clinical diagnosis of Open-Angle Glaucoma for at least 6 months and currently treated with a monotherapy hypotensive medication

Exclusion Criteria:

- Prior angle surgery in the study eye, severe visual field loss in either eye, and any other form of glaucoma besides open-angle glaucoma

Study Design

Allocation: Randomized, Intervention Model: Parallel Assignment, Masking: Double Blind (Subject, Outcomes Assessor), Primary Purpose: Treatment

Related Conditions & MeSH terms

Intervention

Drug:
• Anecortave Acetate
Low dose Sustained release depot suspension
• Anecortave Acetate
Middle dose Sustained release depot suspension
• Anecortave Acetate
High dose Sustained release depot suspension
• Placebo
Placebo treatment with vehicle

Locations
Country Name City State
n/a

Sponsors (1)
Lead Sponsor Collaborator
Alcon Research

Outcome
Type Measure Description Time frame Safety issue
Primary Mean Intraocular Pressure 6 months No
Secondary Percent of patients with therapeutic benefit, number and percent of treatment failure and time to treatment failure 6 months No
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