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Open-Angle Glaucoma clinical trials

View clinical trials related to Open-Angle Glaucoma.

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NCT ID: NCT00443924 Completed - Ocular Hypertension Clinical Trials

Study of INS115644 Ophthalmic Solution in Subjects With Ocular Hypertension or Glaucoma

Start date: March 2007
Phase: Phase 1
Study type: Interventional

The purpose of this trial is to evaluate the safety and tolerability of INS115644 Ophthalmic Solution in subjects with bilateral ocular hypertension or early primary open angle glaucoma and to investigate the intraocular pressure lowering effects of INS115644 Ophthalmic Solution.

NCT ID: NCT00430287 Completed - Open Angle Glaucoma Clinical Trials

Does the Optic Disc Grading Done Visually by Your Doctor Agree With Optic Nerve Testing Which is Done by Machines?

Start date: March 2007
Phase: N/A
Study type: Observational

The purpose of this study is to determine how well the DDLS (Disc Damage Likelihood Scale) (which is a method used by the eye doctor to evaluate how healthy the optic nerve is) measures up to the standard glaucoma tests: OCT (Optical Coherence Tomography), the HRT (Heidelberg Retinal Tomography) and the HVF (Humphrey Visual Field).

NCT ID: NCT00397241 Completed - Open-angle Glaucoma Clinical Trials

24-hour Study of Dorzolamide/Timolol and Latanoprost/Timolol Fixed Combinations

Start date: September 2006
Phase: Phase 4
Study type: Interventional

The primary objective of this crossover trial is to compare the 3-month mean 24-hour intraocular pressure (IOP) control and safety of dorzolamide/timolol fixed combination (DTFC) given twice daily, versus latanoprost/timolol fixed combination (LTFC) given in the evening and placebo given in the morning, versus adjunctive therapy with DTFC given twice daily and latanoprost 0.005% given once in the evening in open-angle glaucoma patients who are insufficiently controlled with latanoprost monotherapy.

NCT ID: NCT00372931 Completed - Ocular Hypertension Clinical Trials

A Phase II Study of AL-37807 to Treat Open-Angle Glaucoma or Ocular Hypertension

Start date: May 2006
Phase: Phase 2
Study type: Interventional

The purpose of this study is to determine whether AL-37807 is safe and effective in treating patients with open-angle glaucoma or ocular hypertension

NCT ID: NCT00362622 Completed - Open Angle Glaucoma Clinical Trials

Determinants of Compliance With Glaucoma Therapy

Start date: October 2005
Phase: N/A
Study type: Observational

To determine the association between medical, demographic, socioeconomic, and therapeutic differences on compliance with topical glaucoma therapy using the Travalert device.

NCT ID: NCT00326092 Completed - Ocular Hypertension Clinical Trials

A Study of a Glaucoma Therapy to Treat Open-Angle Glaucoma or Ocular Hypertension

Start date: May 2006
Phase: Phase 2
Study type: Interventional

The purpose of this study is to assess the comfort of a glaucoma therapy in patients with open-angle glaucoma or ocular hypertension

NCT ID: NCT00326066 Completed - Open-Angle Glaucoma Clinical Trials

A Study of the iStent in Combo With Cataract Surgery in Newly Diagnosed Open Angle Glaucoma or OH Patients.

Start date: February 2005
Phase: N/A
Study type: Interventional

The purpose of this study is to evaluate the safety and efficacy of the iStent trabecular micro-bypass stent in reducing intraocular pressure (IOP) in subjects with newly diagnosed open-angle glaucoma and subjects diagnosed with Ocular hypertension.

NCT ID: NCT00326040 Completed - Open-Angle Glaucoma Clinical Trials

A Study of the Glaukos Trabecular Micro-Bypass Stent in Refractory Open Angle Glaucoma Subjects

Start date: April 2003
Phase: Phase 4
Study type: Interventional

The purpose of this study is to evaluate the safety and efficacy of the iStent trabecular micro-bypass stent in reducing intraocular pressure (IOP) in refractory open-angle glaucoma subjects.

NCT ID: NCT00326014 Completed - Open-Angle Glaucoma Clinical Trials

A Study of the Trabecular Micro-Bypass Stent in Combination With Cataract Surgery in Open Angle Glaucoma Subjects.

Start date: April 2003
Phase: Phase 4
Study type: Interventional

To evaluate the safety and efficacy of a new trabecular bypass that is implanted in conjunction with cataract surgery in open angle glaucoma subjects.

NCT ID: NCT00323284 Completed - Open-Angle Glaucoma Clinical Trials

A Study of the Trabecular Micro-bypass Stent in Combination With Cataract Surgery in Subjects With Open Angle Glaucoma

Start date: June 2005
Phase: Phase 3
Study type: Interventional

The purpose of this study is to evaluate the safety and efficacy of the iStent trabecular micro-bypass stent in reducing intraocular pressure (IOP) in subjects with open-angle glaucoma or ocular hypertension and co-existing cataract.