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Clinical Trial Summary

Botulinum toxin has been widely approved and utilized in the treatment of complex abdominal wall hernias. Botulinum toxin has been only randomly studied in the treatment of open abdomen.


Clinical Trial Description

30 consecutive patients who have open abdomen for any indication, will have 300 IU botulinum toxin injected in three spots in either sides of the abdomen within 72 hours of the start of open abdomen. The hypothesis is botulinum toxin relaxes abdominal wall musculature to ensure better and faster closure of the open abdomen. ;


Study Design


Related Conditions & MeSH terms


NCT number NCT04283916
Study type Observational [Patient Registry]
Source University of Oulu
Contact Elisa Mäkäräinen-Uhlbäck, M.D.
Phone +358505794011
Email elisa.makarainen-uhlback@ppshp.fi
Status Recruiting
Phase
Start date February 21, 2020
Completion date August 2024

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