Artificial Oocyte Activation Comparing Tow Different Agents

Oocyte Fertilization Clinical Trial

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT02424214
• Other study ID #: IbnSina Oocyte activation
• Status: Completed
• Phase: N/A
• First received: April 18, 2015
• Last updated: February 15, 2018
• Start date: April 2015
• Est. completion date: January 2016

Study information

• Verified date: February 2018
• Source: Ibn Sina Hospital
• Contact: n/a
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

Comparing the efficacy of tow factors for artificial Oocyte Activation for poor quality Oocytes and Teratozoospermia patients.

Description:

The IVF outcome had been varied widely with a good portion of total fertilization failure even after the most advanced procedure for this group of patient Intracytoplasmic Sperm Injection, many factors that had been tested for assisting the failed group of patient to be fertilized artificially like Ca Ionophore, Strontium Chloride and others but we decide to compare the clinically proven factors for the efficacy and safety in a well randomized clinical trial and monitor the embryogenesis and pregnancy within the 2 groups.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 450
• Est. completion date: January 2016
• Est. primary completion date: January 2016
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: Female
• Age group: 18 Years to 40 Years

Eligibility

Inclusion Criteria:

• previous fertilization failure

• poor quality Oocytes

• poor sperms

Exclusion Criteria:

• normal patients

Related Conditions & MeSH terms

• Oocyte Fertilization

Intervention

Other:
• Artificial Oocyte activation

Drug:
• Ca Ionophore

• Strontium Chloride

Locations

Country	Name	City	State
Bahrain	Al Barka fertility center	Manama
Egypt	Banon Fertility Center	Assiut
Egypt	Ibnsina IVF center	Sohag

Sponsors (3)

Lead Sponsor	Collaborator
Ibn Sina Hospital	Al Baraka Fertility Hospital, Banon IVF Center Assiut, Egypt

Countries where clinical trial is conducted

Bahrain,  Egypt, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Pregnancy rate ( % )		9 months
Secondary	Blastocyst rate ( % )		9 months