Spread of Dermatophytes Among Families

Onychomycosis Clinical Trial

Official title:

Demonstration of the Spread of Dermatophytes Through Casual Contact Among Family Household Members

Clinical Trial Details — Status: Recruiting

Administrative data

• NCT number: NCT00233493
• Other study ID #: CSFO327KUS16
• Status: Recruiting
• Phase: N/A
• First received: October 3, 2005
• Last updated: October 3, 2005
• Start date: March 2005
• Est. completion date: February 2006

Study information

• Verified date: November 2004
• Source: University Hospital Case Medical Center
• Contact: Mahmoud A Ghannoum, PhD
• Phone: 216-844-8580
• Email: mag3[@]case.edu
• Is FDA regulated: No
• Health authority: United States: Institutional Review Board
• Study type: Observational

Clinical Trial Summary

The objective is to demonstrate person-to-person spread of dermatophytes of the skin and nails among family members, as measured by fungal culture and DNA typing of the dermatophytes isolated.

Description:

Enrolled families consist of at least two members over the age of 14. Once the index person is examined and a dermatophyte is isolated from either toenail or foot scale, other family members are examined and cultured. All dermatophyte isolates obtained from each family unit are compared using DNA typing and restriction length polymorphism (RFLP) to determine whether family members share the same organism or were infected by an outside source.

Recruitment information / eligibility

• Status: Recruiting
• Enrollment: 150
• Est. completion date: February 2006
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: Both
• Age group: 14 Years and older

Eligibility

Inclusion Criteria: positive dermatophyte culture

Exclusion Criteria:

• use of antifungal agents, either oral or topical

Study Design

Observational Model: Defined Population, Time Perspective: Longitudinal

Related Conditions & MeSH terms

• Onychomycosis
• Tinea Pedis

Locations

Country	Name	City	State
United States	Neil Korman, MD	Cleveland	Ohio

Sponsors (2)

Lead Sponsor	Collaborator
University Hospital Case Medical Center	Novartis

Country where clinical trial is conducted

United States,