Clinical Trial Details
— Status: Not yet recruiting
Administrative data
| NCT number |
NCT06042868 |
| Other study ID # |
Oliguria and anuria managment |
| Secondary ID |
|
| Status |
Not yet recruiting |
| Phase |
N/A
|
| First received |
|
| Last updated |
|
| Start date |
September 2023 |
| Est. completion date |
September 2024 |
Study information
| Verified date |
September 2023 |
| Source |
Assiut University |
| Contact |
Hager Abdel Nasser Hussein, Master degree at nursing |
| Phone |
01142347873 |
| Email |
Hgogonono90[@]gmail.com |
| Is FDA regulated |
No |
| Health authority |
|
| Study type |
Interventional
|
Clinical Trial Summary
This study is aim to evaluate the effect of implementing emergency nursing protocol of
obstructive anuria and oliguria on critically ill patients' outcomes.
Description:
Obstructive anuria is defined as a total cessation of diuresis or a volume of less than 200
ml /24 hours or 0 mL/12 h. Oliguria is defined as a urine output that is less than 400 mL/24
h or less than 17 mL/h, due to unilateral or bilateral blockage of a single anatomical or
functional kidney. It is rapidly the cause of acute renal failure, endangering the vital
prognosis in the short term and requiring emergency treatment in a specialized environment,
whatever its etiology (Afifi R, et al., 2022).
Obstructive anuria and oliguria constitutes a major cause for surgical acute kidney injury
(AKI) due to several diseases as cervical cancer, urinary stone, bladder cancer, urinary
tract stenosis, and iatrogenic causes. However, Obstructive anuria and oliguria management
varies between each case; the treatment of choice is based on each patient's condition. We
discovered that a proper management of obstructive anuria resulted in a low mortality rate as
well as restoration of renal function in most patients (Wicaksono F, et al., 2021).
Anuria /Oliguria is frequently observed in the perioperative period and may be the
consequence of hypovolemia and/or pain, both triggering the sympathetic nervous system, which
in turn lead to activation of the renin-angiotensin-aldosterone system with ensuing oliguria.
However, oliguria may also represent a warning of deteriorating renal function, especially in
critically ill patients (Vincent JL and et al., 2020).
2
There are many complications from anuria and oliguria as cardiovascular complications include
congestive heart failure, pulmonary edema, and hypertension, mainly as a result of salt and
water retention. Gastrointestinal complications as anorexia, nausea, vomiting and
gastrointestinal bleeding. Neurologic complications as confusion and seizures may develop in
the course of acute oliguria. Impaired defenses and responses against infection due to uremia
and inappropriate use of antibiotics may contribute to the high degree of infectious
complications. Percutaneous nephrostomy is an excellent initial procedure to relieve
obstruction with minimal complications. The second choice is renal dialysis for deteriorated
patients (Rachid M, et al., 2020).
There is a critical role of nurse for taking history for oliguria and anuria as total volumes
of urine in 24 h, color of urine, accompanying symptoms as (frequency, urgency and dysuria),
special food or drugs as (nephrotoxic drugs, chemicals, eating raw fish guts); history of
relevant diseases as (hemorrhoea, shock, heart failure, renal percussive pain, high fever,
etc.) ; Past history including respiratory infection, angina, chronic nephritis, urinary
calculus, prostate hyperplasia; travelling history as (epidemic hemorrhagic fever or epidemic
area) should be pay attention. Critical care nurse must monitor hemodynamic parameters, signs
of dehydration or fluid overload, fluids balances and duration of oliguria
