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Clinical Trial Summary

The aim of this study is to compare the efficacy of calcium gluconate infusion versus cabergoline in the prevention of ovarian hyperstimulation syndrome (OHSS) in patients pretreated with GnRH agonist long protocol who are at high risk for OHSS.


Clinical Trial Description

Ovarian hyperstimulation syndrome (OHSS) is a serious complication of assisted reproduction.

Previous studies revealed that calcium gluconate infusion reduced the risk of OHSS. Other studies revealed that cabergoline (potent dopamine receptor agonist on D2 receptors)was effective in preventing OHSS.

The aim of this study is to compare the efficacy of calcium gluconate infusion versus cabergoline in the prevention of ovarian hyperstimulation syndrome (OHSS) in patients pretreated with GnRH agonist long protocol who are at high risk for OHSS. ;


Study Design


Related Conditions & MeSH terms

  • OHSS
  • Ovarian Hyperstimulation Syndrome

NCT number NCT02875587
Study type Interventional
Source Aljazeera Hospital
Contact
Status Completed
Phase Phase 2
Start date October 2016
Completion date December 2018

See also
  Status Clinical Trial Phase
Recruiting NCT02358421 - Prediction of High Ovarian Response After Assisted Reproductive Techniques N/A
Completed NCT01984320 - Cabergoline and Coasting to Prevent OHSS N/A
Completed NCT01709942 - Use of Degarelix in Controlled Ovarian Hyperstimulation (COH) Protocol for Women With PoliCystic Ovarian Syndrome (PCOS) Phase 3
Completed NCT02148393 - Implantation Enhancement by Elective Cryopreservation of All Viable Embryos N/A
Recruiting NCT02461875 - Cabergoline Versus GnRH Antagonist Rescue and Cabergoline in the Prevention of Ovarian Hyperstimulation Syndrome Phase 2