OCD Clinical Trial
Official title:
Pilot Study to Evaluate Escitalopram in Obsessive-compulsive Disorder
This study will determine the safety and effectiveness of escitalopram (Lexapro)in treating obsessive-compulsive disorder (OCD) symptoms.
OCD is a chronic and disabling disorder for which Selective Serotonin Reuptake
Inhibitor(SSRI) drugs can be effective. The purpose of this study is to evaluate the effects
of an SSRI, escitalopram, in OCD patients.
This study will last 16 weeks and will comprise 2 phases. Phase 1 is an open label in which
all participants will receive daily escitalopram for 8 weeks. Those who have responded to
treatment at the end of the 8 weeks will be randomly assigned to either continue or
discontinue their treatment for an additional 8 weeks. Those who do not respond to treatment
at the end of Phase 1 will discontinue the study and be offered three free visits with a
study clinician or referred elsewhere for treatment, based on the their preference. Study
visits are made at baseline, and at Weeks 1, 2, 4, and 8 in Phase 1 and Weeks 12 and 16 in
Phase 2.
;
Allocation: Randomized, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Parallel Assignment, Masking: Double Blind (Subject, Investigator, Outcomes Assessor), Primary Purpose: Treatment
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