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Steroids for Pediatric Apnea Research in Kids — SPARK  

Obstructive Sleep Apnea Syndrome Clinical Trial

Official title:
Utility of Nasal Steroids for Treatment of Childhood Obstructive Sleep Apnea

Clinical Trial Summary

This double-blind, randomized controlled trial will evaluate the use of nasal corticosteroids for the treatment of the childhood obstructive sleep apnea syndrome (OSAS). Efficacy, duration of action and side-effects will be determined.

Clinical Trial Description

Several studies have suggested that Nasal corticosteroids (NCS) or leukotriene antagonists may be effective in the treatment of childhood OSAS. However, these studies have been limited by factors such as small size, lack of randomization and blinding, short-term follow-up, involvement of children with only very mild OSAS, and/or lack of stratifying for the presence of atopy. Therefore, investigators will plan a randomized controlled trial evaluating the efficacy and safety of NCS vs placebo in children with mild to moderate OSAS. The overall hypothesis is that NCS will be safe and efficacious in the treatment of mild to moderate childhood OSAS, particularly in children with asthma/atopy, but will require ongoing maintenance therapy. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT02180672
Study type Interventional
Source Children's Hospital of Philadelphia
Contact
Status Completed
Phase Phase 3
Start date September 2014
Completion date October 30, 2021
View Details
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