Obsessive-Compulsive Disorder Clinical Trial
Official title:
Neural Correlates of Compulsivity
NCT number | NCT05195476 |
Other study ID # | 7867 |
Secondary ID | |
Status | Completed |
Phase | |
First received | |
Last updated | |
Start date | December 17, 2021 |
Est. completion date | February 28, 2024 |
Verified date | May 2024 |
Source | Columbia University |
Contact | n/a |
Is FDA regulated | No |
Health authority | |
Study type | Observational |
This study aims to collect data from individuals with obsessive-compulsive disorder (OCD) and healthy controls in order to clarify how learning strategies are employed differently by individuals with compulsive psychopathology and healthy individuals. Behavioral and electroencephalogram (EEG) data will be collected during one experimental reinforcement learning tasks from participants diagnosed with OCD (n = 30) and healthy controls (n = 30). Computational modeling, an advanced data analytic approach that can directly link neural measures with behavior, will be used to quantify learning processes. These parameters then will be related to measures of neural events obtained using EEG, a neuroimaging method that has high temporal resolution, to test for evidence of neurocognitive alterations.
Status | Completed |
Enrollment | 41 |
Est. completion date | February 28, 2024 |
Est. primary completion date | February 28, 2024 |
Accepts healthy volunteers | Accepts Healthy Volunteers |
Gender | All |
Age group | 18 Years to 50 Years |
Eligibility | Inclusion Criteria: - Between 18-50 years of age - English-speaking - Capacity to provide informed consent - Primary diagnosis of OCD with at least moderate severity Exclusion Criteria: - Current or lifetime history of psychiatric disorders other than OCD that may increase the risk of participation - History of any significant medical condition that may increase the risk of participation - Alcohol or substance use disorder in the past year - Exposure and response prevention for OCD within the last six weeks - Currently taking psychotropic medication |
Country | Name | City | State |
---|---|---|---|
United States | New York State Psychiatric Institute | New York | New York |
Lead Sponsor | Collaborator |
---|---|
Columbia University | International OCD Foundation |
United States,
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | Neural Activity | EEG will be recorded while participants complete computerized reinforcement learning tasks at one study visit | One-time study visit |
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