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Cognitive Training in Obsessive Compulsive Disorder — CTOCD  

Obsessive-Compulsive Disorder Clinical Trial

Official title:
Cognitive Training in Patients With Obsessive Compulsive Disorder

Clinical Trial Summary

This unique study will allow us to observe the neural correlates associated with working memory in an obsessive compulsive disorder (OCD) paradigm. We believe that developing working memory in participants suffering with OCD will reduce the severity of their symptomology. This will allow a greater understanding into the functioning of these participants which in turn presents with treatment possibilities.

Clinical Trial Description

It is currently unclear whether cognitive training using a working memory task, is effective in reducing obsessive-compulsive symptoms and neuropsychological deficits in patients with OCD. Two groups (OCD and control) will be recruited. Both groups will undergo an intervention consisting of 8 weeks of cognitive training. Working memory, neuropsychological functioning and OCD symptomatology will be assessed pre and post-treatment, in both groups. Furthermore neuroimaging using functional magnetic resonance imaging (fMRI) will be conducted at baseline as well as at the end of the 8 week period in both groups. The scan will serve to show any structural or functional changes in the frontostriatal area involved with working memory. To our knowledge, this is one of the first studies to date to examine whether cognitive training improves symptoms in OCD. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT02818088
Study type Interventional
Source University of Stellenbosch
Contact
Status Terminated
Phase N/A
Start date February 2016
Completion date December 2019
View Details
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