Obsessive Compulsive Disorder Clinical Trial
Official title:
Developing Effective Response Inhibition Training for Symptom Relief in Obsessive-Compulsive and Related Disorders and Trichotillomania
Obsessive-compulsive disorder (OCD) and its related disorders (e.g., trichotillomania) are characterized by the marked difficulty in inhibiting unwanted or inappropriate responses. There is compelling evidence that poor response inhibition is a core cognitive feature of OCD and its related disorders, but no effective intervention exists that directly attempts to address this problematic cognitive deficiency. This study will examine the feasibility and clinical utility of a computerized cognitive training program designed to improve response inhibition among individuals diagnosed with OCD or trichotillomania.This training program offers systematic practice of response inhibition in the form of a 40-level computer game. Individuals with these conditions will be randomized to either 8 sessions of (a) computerized response inhibition training (RIT) or (b) placebo computer training (PLT). We hypothesize that RIT will outperform PLT in improving response inhibition capabilities and reducing relevant clinical symptoms. In sum, this project is expected to generate important knowledge to guide the development of effective computer-based treatment approaches that may help reduce critical problems of existing treatments such as suboptimal patient retention and treatment under-utilization, thereby improving overall treatment response rates among individuals suffering from OCD and related conditions.
n/a
Status | Clinical Trial | Phase | |
---|---|---|---|
Recruiting |
NCT04631042 -
Developing Brain, Impulsivity and Compulsivity
|
||
Completed |
NCT02855580 -
Integrating Pharmacogenomic Testing Into a Child Psychiatry Clinic
|
||
Completed |
NCT02229903 -
An Evaluation of the Safety and Efficacy of the dTMS Treatment for OCD
|
N/A | |
Completed |
NCT02202915 -
CBT for Pediatric OCD: Community Training Pilot
|
N/A | |
Completed |
NCT01794156 -
Evaluation of a Cognitive Therapy (Inference-based-therapy) for the Treatment of Obsessional Compulsive Disorder
|
N/A | |
Completed |
NCT02089984 -
Web Based Therapist Training on Cognitive Behavior Therapy for Anxiety Disorders
|
N/A | |
Completed |
NCT01348529 -
Internet Cognitive Behavior Therapy (CBT) for Obsessive Compulsive Disorder (OCD)
|
N/A | |
Recruiting |
NCT00965211 -
Evaluation of the HBDL Coil Transcranial Magnetic Stimulation (TMS) Device - Safety and Feasibility Study for the Treatment of Tourette Syndrome
|
N/A | |
Completed |
NCT00723060 -
Comparison of Effects Between Conventional Dose and High Dose Escitalopram on Clinical Improvement in Patients With Obsessive-compulsive Disorder
|
Phase 4 | |
Completed |
NCT01172873 -
D-Cycloserine Augmentation to CBT With Exposure and Response Prevention in Adults and Adolescents With OCD
|
N/A | |
Not yet recruiting |
NCT00743834 -
Cost-Effectiveness of Adding Web-Based Cognitive-Behavioral Therapy (CBT) to Luvox CR for Obsessive Compulsive Disorder (OCD)
|
Phase 4 | |
Completed |
NCT02421315 -
Overlapping Neural Circuits in Pediatric OCD
|
N/A | |
Completed |
NCT02194075 -
Methylphenidate Hydrochloride Controlled-Release Tablets Augmentation Strategy for Patients With Obsessive Compulsive Disorder
|
Phase 4 | |
Completed |
NCT01981317 -
Stepped Care Cognitive Behavioral Therapy for Pediatric Obsessive Compulsive Disorder
|
N/A | |
Completed |
NCT01686087 -
Attaining and Maintaining Wellness in Obsessive-compulsive Disorder
|
N/A | |
Completed |
NCT01331876 -
Modification of Cerebral Activity of Obsessive Compulsive Disorder (OCD) Patients During Cognitive and Behavioral Therapy
|
N/A | |
Terminated |
NCT00997087 -
A Randomized, Double-Blind, Placebo-Controlled Trial of Flumazenil for the Treatment of Obsessive Compulsive Disorder
|
Phase 2 | |
Completed |
NCT00533806 -
Comparing the Effectiveness of Two Family-based Therapies in Treating Young Children With Obsessive-Compulsive Disorder
|
Phase 3 | |
Completed |
NCT00517244 -
Evaluating Parenting Styles and Child Temperament Associated With Child Anxiety Disorders
|
N/A | |
Completed |
NCT00169377 -
Subthalamic Nucleus (STN) Stimulation and Obsessive-Compulsive Disorder (OCD)
|
Phase 1/Phase 2 |