Attentional Bias Modification Treatment in OCD

Obsessive-compulsive Disorder Clinical Trial

Official title:

Attentional Bias and Attentional Bias Modification Treatment in Obsessive-compulsive Disorder

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT02014194
• Other study ID #: 13674113.2.0000.0068
• Status: Completed
• Phase: N/A
• First received: November 25, 2013
• Last updated: January 23, 2018
• Start date: November 2013
• Est. completion date: December 2016

Study information

• Verified date: January 2018
• Source: University of Sao Paulo
• Contact: n/a
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

Obsessive-compulsive disorder is a chronic condition. Even with proper treatment, no significant improvement is reached in about 30% to 40% of patients. Thus, the development of new treatment strategies is necessary. The attentional bias - ability to aversive stimuli in capturing the attention of an individual compared to a neutral stimulus - has been extensively studied. Already training attentional bias modification has been shown effective in reducing anxiety present in other anxiety disorders.This project aims to: 1 - generate knowledge on attentional bias in individuals with OCD through the use of a standardized protocol developed for OCD; 2 - available to the scientific community the first specific paradigm for the study of attentional bias in OCD patients, 3 - test the effectiveness of a training protocol for reversing attentional bias in individuals with OCD.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 30
• Est. completion date: December 2016
• Est. primary completion date: December 2016
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: All
• Age group: 18 Years to 65 Years

Eligibility

Inclusion Criteria: - 30 patients with obsessive-compulsive diagnosis according to DSM-V (with cleaning and or symmetry dimensions)

• 30 health controls

Exclusion Criteria: - doing any kind of behavioral therapy in the moment

Related Conditions & MeSH terms

• Obsessive-Compulsive Disorder

Intervention

Behavioral:
• attentional bias modification treatment
The attentional bias modification treatment is a behavioral computerized program (software e-prime)

Locations

Country	Name	City	State
Brazil	University of Sao Paulo Medical School	Sao Paulo

Sponsors (1)

Lead Sponsor	Collaborator
Roseli Shavitt

Country where clinical trial is conducted

Brazil, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Percentage of reduction of attentional bias		Patients will be followed an expected average of 7 weeks (baseline, 2 sessions per week - totalizing 5 weeks, 10 sessions and a session after end of treatment). Measures of attentional bias will be assessed in baseline, session 5 and after session 10.
Secondary	Reduction of anxiety symptoms		Baseline, session 5 and end of treatment (after session 10) (expected average of 7 weeks)