Internet-based Cognitive Behavior Therapy (CBT) for Obsessive Compulsive Disorder (OCD)

Obsessive Compulsive Disorder Clinical Trial

Official title:

Internet-based Cognitive Behavior Therapy for Obsessive Compulsive Disorder: A Randomized Controlled Trial

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT01347099
• Other study ID #: OCD-S
• Status: Completed
• Phase: Phase 2
• First received: May 2, 2011
• Last updated: March 19, 2018
• Start date: February 2011
• Est. completion date: June 2011

Study information

• Verified date: May 2011
• Source: Karolinska Institutet
• Contact: n/a
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

Cognitive behavior therapy (CBT) is an effective treatment for obsessive compulsive disorder (OCD) but there is a lack of properly trained CBT therapists. One possible treatment alternative is Internet-based CBT (ICBT) with minimal therapist input. The aim of this study was therefore to evaluate ICBT for OCD.

Description:

This is a randomized controlled trial with 101 participants. The control group receives support therapy on demand on the Internet.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 101
• Est. completion date: June 2011
• Est. primary completion date: June 2011
• Accepts healthy volunteers: No
• Gender: All
• Age group: 18 Years and older

Eligibility

Inclusion Criteria:

• Primary diagnosis of obsessive compulsive disorder (OCD)

• At least 18 years old

• Able to read and write in swedish

• Computer access

Exclusion Criteria:

• other primary diagnosis

• substance abuse,

• psychosis,

• bipolar disorder,

• suicidal ideation,

• adjusted pharmacological treatment the last two months

• current psychological treatment for OCD,

• been treated with CBT the last two years,

• serious somatic disease,

• Y---BOCS>31

• hoarding as primary OCD subtype

Related Conditions & MeSH terms

• Disease
• Obsessive Compulsive Disorder
• Obsessive-Compulsive Disorder

Intervention

Behavioral:
• Internet-based cognitive behavior therapy
Internet-delivered CBT. Contact with therapist thru an e-mail system. 10 weeks
• Support therapy on Internet
Internet-delivered support therapy. Contact with therapist thru an e-mail system. 10 weeks

Locations

Country	Name	City	State
Sweden	Psykiatri Sydväst	Stockholm

Sponsors (1)

Lead Sponsor	Collaborator
Karolinska Institutet

Country where clinical trial is conducted

Sweden, 

References & Publications (1)

Andersson E, Enander J, Andrén P, Hedman E, Ljótsson B, Hursti T, Bergström J, Kaldo V, Lindefors N, Andersson G, Rück C. Internet-based cognitive behaviour therapy for obsessive-compulsive disorder: a randomized controlled trial. Psychol Med. 2012 Oct;42 — View Citation

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Change from Baseline of obsessions and compulsions after 10 weeks and at 3- and 12 months after treatment.	Yale Brown Obsessive Compulsive Scale (Y-BOCS)	Two weeks before treatment, 10 weeks after treatment starts, 3 and 12 months after treatment has ended
Secondary	Change from Baseline of obsessions and compulsions after 10 weeks and at 3- and 12 months after treatment.	Obsessive Compulsive Scale - Revised (OCI-R)	Two days before treatment, once per week for 10 weeks after treatment starts, 3 and 12 months after treatment has ended
Secondary	Change from Baseline of obsessions and compulsions after 10 weeks and at 3- and 12 months after treatment.	Dimensional Obsessive Compulsive Scale (DOCS)	Two weeks before treatment, 10 weeks after treatment starts, 3 and 12 months after the treatment has ended
Secondary	Change from Baseline of depressive symptoms after 10 weeks and at 3- and 12 months after treatment.	Montgomery Asberg Depression Rating Scale	Two weeks before treatment, 10 weeks after treatment starts, 3 and 12 months after treatment has ended
Secondary	Change from Baseline of meta cognitions after 10 weeks and at 3- and 12 months after treatment.	Obsessive Beliefs Scale	Two weeks before treatment, 10 weeks after treatment starts, 3 and 12 months after treatment has ended
Secondary	Change from Baseline of quality of life after 10 weeks and at 3- and 12 months after treatment.	Euroqol	Two weeks before treatment, 10 weeks after treatment starts, 3 and 12 months after treatment has ended