Obesity, Metabolically Benign Clinical Trial
Official title:
Effects of MET-3 and MET-5 on Gut Microbiome and Metabolic Function in Men and Women With Hypertriglyceridemia
The purpose of this pilot study is to determine the effects of two human microbiome formulations (MET-3 and MET-5) on fasting serum TG concentration.
Obesity is a condition characterized by an excess amount of body fat, and is defined as a
body mass index (BMI) of 30 kg/m² or greater. The rising prevalence of obesity in all parts
of the world is of great public health concern due to the fact that obesity is associated
with many causes of morbidity and mortality. Excess body fat accumulates when energy intake
is greater than energy expenditure and recently, the role of the colonic microbiome has been
highlighted as a potential contributor to energy balance. The obese microbiome is suggested
to promote obesity due to an excess production of short-chain fatty acids, and, thus,
increased colonic energy availability.
The purpose of this pilot study is to determine the effects of two human microbiome
formulations (MET-3 and MET-5) on fasting serum TG concentration.
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