Obesity and Mortality

Obesity and Overweight Clinical Trial

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT01889225
• Other study ID #: R01-DK076771-Aim1A
• Secondary ID: R01DK076771
• Status: Completed
• Phase: N/A
• First received: June 20, 2013
• Last updated: August 21, 2014
• Start date: January 2008
• Est. completion date: December 2013

Study information

• Verified date: August 2014
• Source: University of Alabama at Birmingham
• Contact: n/a
• Is FDA regulated: No
• Health authority: United States: National Institute of HealthUnited States: UAB Institutional Review Board
• Study type: Observational

Clinical Trial Summary

Previous analyses of the National Health and Nutrition Examination Survey have suggested that the mortality rate associated with obesity has decreased over calendar time in the U.S. population, potentially due to improvements in the medical care of obesity and its associated diseases. The primary aim of this project is to evaluate whether this reduction in the detrimental association of obesity with mortality rate over calendar time is supported by other data from U.S. prospective studies.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 311982
• Est. completion date: December 2013
• Est. primary completion date: December 2013
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: Both
• Age group: 18 Years and older

Eligibility

Inclusion Criteria:

• U.S. based studies with at least 1500 subjects

• At least 5 years of mortality follow-up

• BMI measured or self-reported available at 2 or more separate calendar time

• Subjects varied in age at baseline

Exclusion Criteria:

• Any study that does not meet the inclusion criteria was excluded

Study Design

Observational Model: Cohort, Time Perspective: Prospective

Related Conditions & MeSH terms

• Obesity and Overweight

Locations

Country	Name	City	State
n/a

Sponsors (2)

Lead Sponsor	Collaborator
University of Alabama at Birmingham	National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Change in Years of Life Lost Associated with Standard BMI categories Over Calendar Time		Between 1960 and 2000 (up to 40 years)	No
Secondary	Change in Adjusted Hazard Ratio Over Calendar Time for Standard BMI Categories		Between 1960 and 2000 (up to 40 years)	No