Exclusive Enteral Nutrition in Patients With Ileocaecal Crohn's Disease

Status Recruiting

Clinical Trial Summary

Inflammatory bowel diseases are chronic and progressive entities, triggered by exposure to environmental factors in individuals with a genetic background. One of the most common environmental factors is the type of diet which is a key influencer on pathogenesis. Nutrients alter the intestinal microbiota, thus changing the intestinal permeability. The Western-type diet encompasses sugar, fat, and protein-rich products that have some deleterious effects on the intestinal microbiome compared to the plant-based Mediterranean-type diet. Based on this fact, diet-based therapeutic efforts have been used extensively in pediatric Crohn's disease patients and there is strong evidence that exclusive enteral nutrition (EEN) is as effective as corticosteroids to induce both clinical and endoscopic remission but this treatment strategy is underutilized in adults.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT04921033
Study type	Interventional
Source	Duzce University
Contact	Salih Tokmak
Phone	0905052532698
Email	salihtokmak@duzce.edu.tr
Status	Recruiting
Phase	Phase 3
Start date	March 1, 2021
Completion date	January 1, 2026

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