Sex Differences in Neuropeptide Y Serum, But Not in Fat Intake and Body Mass Index

Nutrient Deficiency Clinical Trial

Official title:

Sex Differences in Neuropeptide Y Serum, But Not in Fat Intake and Body Mass Index

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT04650308
• Other study ID #: USumateraUtara 2
• Status: Completed
• Phase: N/A
• Start date: April 2, 2020
• Est. completion date: September 10, 2020

Study information

• Verified date: November 2020
• Source: Universitas Sumatera Utara
• Contact: n/a
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

One's appetite has a role in controlling food intake and maintaining energy balance, but its effect on body metabolism related to obesity is still questionable. The purpose of this study was to determine the levels of neuropeptide Y in healthy people and to see differences in gender and anthropometric parameters. The hypothesis of this study was that there would be differences in neuropeptide Y levels in groups with gender and anthropometric parameter differences.

Description:

One's appetite has a role in controlling food intake and maintaining energy balance, but its effect on body metabolism related to obesity is still questionable. The purpose of this study was to determine the levels of neuropeptide Y in healthy people and to see differences in gender and anthropometric parameters. The hypothesis of this study was that there would be differences in neuropeptide Y levels in groups with gender and anthropometric parameter differences. This study was a cross-sectional study involving 62 study subjects, male and female, who did not have chronic diseases or metabolic disorders. This research was conducted from April to September 2020. The parameters examined in this study were neuropeptide Y levels and anthropometric parameters. The statistical analysis performed was the Mann-Whitney test to see the differences between groups. The mean age of the research subjects was 40.48 ± 10.85 years, with the same ethnic distribution. The distribution of men and women was more women than men. Based on anthropometric examination, it was found that obesity nutritional status was more common in the female group than in the male group; however, serum neuropeptide Y levels were found to be significantly different between male and female groups (male group was higher).

Recruitment information / eligibility

• Status: Completed
• Enrollment: 62
• Est. completion date: September 10, 2020
• Est. primary completion date: June 17, 2020
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: All
• Age group: 20 Years to 60 Years

Eligibility

Inclusion Criteria:

• healthy groups for Neuropeptide Y Serum diagnosis

Exclusion Criteria:

• Non-healthy groups for Neuropeptide Y Serum diagnosis

Related Conditions & MeSH terms

• Nutrient Deficiency

Intervention

Diagnostic Test:
• Neuropeptide Y examination
This examination was conducted by drawing blood serum from research subjects and performing centrifugation with 2000-3000 revolutions per minute (RPM) for 20 minutes. Furthermore, we carried out blood serum tests to check neuropeptide Y levels using the Human Neuropeptide Y Enzyme-link Immunosorbent Assay (ELISA) kit

Locations

Country	Name	City	State
Indonesia	Faculty of Medicine Universitas Sumatera Utara	Medan	North Sumatra

Sponsors (1)

Lead Sponsor	Collaborator
Universitas Sumatera Utara

Country where clinical trial is conducted

Indonesia, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	levels of neuropeptide Y		up to 2 weeks