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Paclitaxel-trastuzumab in EGFR-mutated NSCLC Patients

NSCLC Clinical Trial

Official title:
Paclitaxel-trastuzumab in EGFR-mutated NSCLC Patients After Progression on TKI-treatment; a Pilot-study

Clinical Trial Summary

This study is a pilot study in EGFR-mutated NSCLC patients who have progressed on standard-dose TKIs. Tumor biopsies will be evaluated for HER2-expression. In case of HER2 expression, patients can participate in the trial after obtaining informed consent.

Patients will be treated with weekly paclitaxel-trastuzumab.

Clinical Trial Description

n/a

Study Design

Allocation: Non-Randomized, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Single Group Assignment, Masking: Open Label, Primary Purpose: Treatment

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT02226757
Study type Interventional
Source VU University Medical Center
Contact Justine Kuiper, MD
Phone 0031204442214
Email jl.kuiper@vumc.nl
Status Not yet recruiting
Phase Phase 2
Start date August 2014
View Details
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