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Immunotherapy Consolidation After Radical Treatment of Synchronous Oligo-metastatic NSCLC — ICARS  

NSCLC Stage IV Clinical Trial

Official title:
Immunotherapy Consolidation After Radical Treatment of Synchronous Oligo-metastatic NSCLC

Clinical Trial Summary

This is a multi-center, double-blind, placebo-controlled randomized phase II study to assess whether continuation of cemiplimab treatment (for up to 12 months) increases progression-free survival (PFS) as compared to placebo in patients with a stage IV, synchronous, oligometastatic non-small cell lung cancer (NSCLC) who have not progressed following 4 cycles of cemiplimab with our without platinum-based chemotherapy and radical treatment. Eligible patients are randomized with a 1:1 ratio to either the cemiplimab or placebo group and will undergo disease assessment (e.g. imaging, blood tests) at regular follow-up visits.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT06219317
Study type Interventional
Source European Organisation for Research and Treatment of Cancer - EORTC
Contact EORTC
Phone +32 2 774 1611
Email eortc@eortc.org
Status Not yet recruiting
Phase Phase 2
Start date October 2024
Completion date January 2030
View Details
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