18F-PD-L1 PET/CT in Nivolumab Treated Patients With NSCLC

Status Recruiting

Clinical Trial Summary

A multicenter single arm biomarker exploration and validation study. Eighty patients with NSCLC that are eligible for first line chemo-immunotherapy, first line nivolumab/ipilimumab or 2nd line and beyond PD-(L)1 immunotherapy monotherapy according to EMA label and national guidelines will be enrolled in this trial. All subjects will undergo a whole body 18F-PD-L1 PET/CT scan before start of nivolumab containing treatment. Patients will continue treatment until disease progression, withdrawal of patient consent or unacceptable toxicity.

Clinical Trial Description

18F-PD-L1 PET/CT scan to predict durable reponse to nivolumab containing treatment in patients with NSCLC ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT03564197
Study type	Interventional
Source	The Netherlands Cancer Institute
Contact	Joop de Langen, MD
Phone	+3120512
Email	j.d.langen@nki.nl
Status	Recruiting
Phase	N/A
Start date	October 25, 2018
Completion date	December 30, 2024

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