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Nose Deformities, Acquired clinical trials

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NCT ID: NCT06163209 Recruiting - Facial Injuries Clinical Trials

Ultrasonography in the Diagnosis of Nasal Fractures

Start date: December 8, 2023
Phase:
Study type: Observational [Patient Registry]

The purpose of this cross-sectional prospective observational study is to determine the efficacy of high-resolution ultrasonography in identifying and characterizing nasal bone fractures in adult patients with recent facial trauma. The primary questions it aims to answer are: - Can high-resolution ultrasonography effectively detect nasal bone fractures? - Is high-resolution ultrasonography capable of indirectly detecting septal fractures? - What are the specificity and sensitivity of high-resolution ultrasonography in comparison to computed tomography scan? Participants will undergo examination and treatment in accordance with current standards for nasal fracture management. Additionally, high-resolution ultrasonography will be performed during the initial physical examination, preceding any therapeutic interventions.

NCT ID: NCT06094348 Recruiting - Clinical trials for Nasal Deformity, Acquired

The Evaluation of Piezo and Endonasal Osteotomy Methods on Postoperative Healing Process in Septorhinoplasty

Start date: May 19, 2023
Phase:
Study type: Observational [Patient Registry]

The goal of this observational study is to compare the effect of Piezo and endonasal osteotomy techniques on the healing process of patients undergoing septorhinoplasty surgery. The main question[s] it aims to answer are: - In which osteotomy technique the edema is lesser? - Which osteotomy technique is better for thick vs thin skinned patients ? In which osteotomy technique the healing process is faster? Participants will be asked to have an ultrasonic measurement of the nasal dorsum preoperatively and at the first, third and tenth months postoperatively. Researchers will compare the thick and thin skinned patients to detect which osteotomy technique is superior in the healing process ( lesser edema and faster healing due to skin thickness measurements)

NCT ID: NCT04579042 Completed - Clinical trials for Nasal Septal Deviation

Cartilaginous Batten Graft Septoplasty in Caudal Septal Deviation

Start date: October 7, 2020
Phase: N/A
Study type: Interventional

To evaluate the clinical outcomes of septoplasty using cartilaginous batten graft in cases with caudal septal deviation as regards the relieve of nasal obstruction and aesthetic results.

NCT ID: NCT04334590 Withdrawn - Cleft Lip Clinical Trials

Fabrication of Sequential Naso-Alveolar Molding Appliances in the Treatment of Cleft Lip/Nose Deformities

Start date: June 8, 2020
Phase:
Study type: Observational

There is a robust body of research suggesting that the use of pre-surgical orthopedic devices prior to definitive cleft lip/nose repair results in significant improvement of facial aesthetics with long term follow up. However, in recent surveys of the cleft centers in the US, only 30% of cleft centers offer PSIOs, and only 13% routinely report its use. Accordingly, thirty percent of centers utilize a two-stage cleft lip/nose repair in the centers' algorithm (1st: lip adhesion; 2nd: final lip repair). The major drawback to a two-stage cleft procedure is the administration of two general anesthetics to an infant before the age of one year. There is a growing amount of evidence that multiple anesthetic experiences before a certain age could affect brain development. It is difficult to make inferences as to why clinicians are not utilizing surgical aids to decrease the size of the cleft width, but even when PSIO is offered, caregivers experience additional, potentially prohibitive challenges. In one study, caregivers traveled an average of 70 miles to visit the nearest cleft center offering pre-surgical orthopedic devices. As these devices are created by hand every 1-2 weeks after seeing the child in clinic, parents are required to travel to clinic multiple times per month. Not surprisingly, infants who were first-born and those who did not have other siblings were more likely to receive pre-surgical orthopedic treatment than infants who were residing with other siblings. Given the benefits of PSIOs and the barriers both to healthcare systems and patients' families associated with PSIOs in its current form, a new form of pre-surgical clinical management is needed. Objectives: 1. Evaluate JHH's current clinical performance in addressing unilateral cleft lip and nasal deformity. 2. Elucidate the difference in preoperative cleft size and in surgical management/outcomes for patients who received PSIOs through 3D-printed devices. 3. Using the above maxillofacial growth data with and without PSIOs, the investigators aim to create an algorithm to predict maxillofacial growth for each individual patient to design pre-sequenced custom PSIO devices.

NCT ID: NCT03726723 Not yet recruiting - Nasal Obstruction Clinical Trials

Effect of a Pre-Operative Local Anesthetic Facial Block on Post-Operative Rhinoplasty Pain

Start date: December 2018
Phase: Phase 4
Study type: Interventional

The specific aim of this study is to determine whether pre-operative treatment with a bupivacaine nerve block can influence post-operative pain and oxycodone usage among rhinoplasty patients. Specifically, we plan to directly compare the reported pain scale, nausea, and oxycodone usage among patients who received the bupivacaine block against those of patients in the saline control condition. These assessments will be documented on day 0 (day of operation) by a nurse in the Post-Anesthesia Care Unit, while the same data points will be collected over the phone by our clinical research coordinator on post-operative days 1, 2 , 3, and 8 following discharge.

NCT ID: NCT03624608 Suspended - Microtia Clinical Trials

Evaluation of the Auryzon Devices in the Optimization of Ear and Nose Reconstruction Procedures

Start date: March 1, 2020
Phase: N/A
Study type: Interventional

This study evaluates the efficacy of the AuryzoN devices in the ear and nose reconstruction surgeries, both in terms of operative time and overall quality of reconstruction. Research participants will undergo reconstruction either using the AuryzoN device or through current methods (traditional manual processing) at the discretion of their surgeon prior to the start of surgery.

NCT ID: NCT02815345 Terminated - Clinical trials for Nose Deformities, Acquired

Objectives and Measures Dimensions Nasal Resistance of Preterm and Term (MODERN)

MODERN
Start date: March 2014
Phase: N/A
Study type: Interventional

During the resuscitation of preterm infants, withdrawal of non-invasive ventilation is difficult. In a recent study in children gestational age <30 weeks of amenorrhea (SA), definitive withdrawal rate from the first attempt to stop the non-invasive ventilation was 32% . In the same study, the median number of attempts before achieving a final withdrawal was 3 for children born before 28 weeks. The reasons for weaning failure are multiple and little studied. It seems that the type of interface used, mask or cannula, having an influence on the effectiveness of non-invasive ventilation . The nasal lesions induced by non-invasive ventilation are not uncommon, regardless of the interface used . In a recent randomized trial, they ranged from 40% to 50% depending on the type of nasal cannula and non-invasive ventilation mode. It is in this case external damage. But we assume that the breakdown causes internal lesions dependent on the pressure, humidity and flow. These factors are likely to generate a nasal obstruction, source intervention nurses who aspire nasal passages more or less traumatic. The nasal cavities are often abused and, because of their key role in breathing, could be involved in the withdrawal of ventilatory failure

NCT ID: NCT02603796 Completed - Clinical trials for Nose Deformities, Acquired

3D Imaging of Neonatal Faces

Start date: October 2015
Phase: N/A
Study type: Observational

Facial scans of newborns will be performed before and after implementation of respiratory support devices such as nasal CPAP. 3D scanned images will be processed by Fisher & Paykel Healthcare Limited. Images will be analyzed for changes or distortion in nasal structure.

NCT ID: NCT02026999 Completed - Clinical trials for Nasal Septum Deviation

Sugammadex Versus Neostigmine Use in Patients Undergoing Septoplasty Operations

Start date: January 2012
Phase: N/A
Study type: Observational [Patient Registry]

The purpose of this study to determine the effectiveness of sugammadex in septoplasty patients whose mask ventilation would be difficult after extubation.

NCT ID: NCT01943929 Recruiting - Headache Clinical Trials

Correlation Between Headaches and Septum and Nasal Mucosa Contact

Start date: November 2012
Phase: N/A
Study type: Observational

Headache is the most common complaint to neurologists. In the 80´s and 90's few papers, with limited number of patients, have proposed the association between nasal septum contact and headache. The International Classification of Headaches Disorders proposed specific diagnostic criteria for this entity. With the major use of CT scans, the contact between nasal mucosa and septum is daily observed in many patients without complaint of headache. The purpose of this study is to determine if there is any correlation between nasal and septum mucosa contact and the prevalence of headache. The investigators hypothesized that no correlation will be found using CT scans in a large series of patients.