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Positron Emission Tomography Imaging of Brain Amyloid in Normal Pressure Hydrocephalus

Normal Pressure Hydrocephalus Clinical Trial

Official title:
A Principal, Prospective, Open-label Biopsy Study to Validate Detection of Cerebral Cortical Amyloid With Flutemetamol (18F) Injection in Normal Pressure Hydrocephalus (NPH) Subjects.

Clinical Trial Summary

To determine the level of association between the quantitative estimates of brain uptake of [18F]flutemetamol and the quantitative immunohistochemical and histochemistry estimates of amyloid levels in frontal lobe biopsy samples obtained from subjects during shunt placement for NPH.

Clinical Trial Description

n/a

Study Design

Endpoint Classification: Safety/Efficacy Study, Intervention Model: Single Group Assignment, Masking: Open Label, Primary Purpose: Diagnostic

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT01092546
Study type Interventional
Source GE Healthcare
Contact
Status Terminated
Phase Phase 3
Start date March 2010
Completion date April 2011
View Details
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