Nonunion Fracture Clinical Trial
Official title:
Treatment of Nonunion of Limb Fracture With Human Amniotic Epithelial Cells（hAECs）
The purpose of this study is to evaluate the efficacy and safety of human amniotic epithelial cells transplant in nonunion of limb fracture patients.
In this study, patients of nonunion after limb fracture will be treated with human amniotic
epithelial cells. Clinical and radiological assessment is performed.
hAECs developing from the epiblast as early as 8 days after fertilization, recent data
reported indicate that hAECs possess proper osteogenic differentiation potential and a
localized modulatory influence on the early tissue remodeling process, making these cells a
promising stem cell source for bone regeneration after fractures.
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| Status | Clinical Trial | Phase | |
|---|---|---|---|
| Withdrawn |
NCT01429012 -
Treatment of Atrophic Nonunion Fractures by Autologous Mesenchymal Stem Cell Percutaneous Grafting
|
Phase 2 | |
| Completed |
NCT01788059 -
The Efficacy of Mesenchymal Stem Cells for Stimulate the Union in Treatment of Non-united Tibial and Femoral Fractures in Shahid Kamyab Hospital
|
Phase 2 |