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Clinical Trial Summary

Nonalcoholic fatty liver disease (NAFLD), defined by fatty infiltration of the liver in the absence of excess alcohol consumption, affects an estimated 30% of adults in the United States. A proportion of people with NAFLD will develop progressive, inflammatory nonalcoholic steatohepatitis (NASH), which can progress to liver cirrhosis and liver failure. NAFLD is expected to be the most common indication for liver transplantation by the year 2020. We hypothesize that among adults with NAFLD, aspirin will reduce intrahepatic lipid content, as quantified by 1H magnetic resonance spectroscopy (1H-MRS).


Clinical Trial Description

n/a


Study Design


Related Conditions & MeSH terms


NCT number NCT04031729
Study type Interventional
Source Massachusetts General Hospital
Contact
Status Completed
Phase Phase 1/Phase 2
Start date September 12, 2019
Completion date February 23, 2023

See also
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