Non-Vital Tooth Clinical Trial
Official title:
Effect of Piroxicam Premedication on Postendodontic Pain in Mandibular Molars With Non-vital Pulp: A Randomized Controlled Trial
The aim of the study is to evaluate the effect of piroxicam (20mg) compared to placebo on post-endodontic pain of single-visit endodontic treatment of non-vital mandibular molars.
- Patients will be clinically and radiographically examined and their eligibility will be
assessed. Eligible patients will be treated in one visit.
- Patients will be randomly assigned to one of 2 groups: experimental group (premedication
with 20 mg of piroxicam) and the control group (premedication with placebo). Each
participant will receive a standard inferior alveolar nerve block injection. After
endodontic treatment, patients will be given postoperative instructions and informed, in
case of pain, to receive ibuprofen 200 mg as rescue medication.
- Postendodontic pain intensity and incidence at the different pain categories (No, mild,
moderate, severe) will be assessed 6, 12, 24, 48, 72 hours and 7 days postoperatively
using a 0-10 numerical rate scale (NRS). Analgesic intake throughout the 7 days will be
recorded.
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| Status | Clinical Trial | Phase | |
|---|---|---|---|
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