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Vebreltinib Plus PLB1004 in EGFR-mutated, Advanced NSCLC With MET Amplification or MET Overexpression Following EGFR-TKI

Non-Small-Cell Lung Cancer Clinical Trial

Official title:
A Phase Ib/II Study of Vebreltinib Plus PLB1004 in EGFR-mutated, Advanced NSCLC With MET Amplification or MET Overexpression Following EGFR-TKI

Clinical Trial Summary

Efficacy and Safety Evaluation of Vebreltinib Plus PLB1004 in EGFR TKI Relapsed MET Amplified or MET Expression in NSCLC

Clinical Trial Description

Open label, multicenter Phase Ib/II clinical study to evaluate the safety, efficacy, and pharmacokinetics of Vebreltinib in combination with PLB1004 in patients with locally advanced or metastatic non-small cell lung cancer with MET overexpression or MET amplification following EGFR-TKI treatment failure. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT06343064
Study type Interventional
Source Avistone Biotechnology Co., Ltd.
Contact Liang Lin
Phone +86-10-84148931
Email linliang@avistonebio.com
Status Recruiting
Phase Phase 1/Phase 2
Start date June 13, 2023
Completion date June 30, 2025
View Details
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