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Clinical Trial Summary

This is a 2:1 randomized multicentre open label phase III study of radiation combined with standard systemic treatment compared with systemic treatment alone in oligometastatic (≤5 metastases) NSCLC. Stratification factors: performance status, gender and systemic strategy. The systemic treatment consists of chemotherapy/chemoimmunotherapy or immunotherapy and is given according to local practice. During the first 3 months of systemic treatment, aiming to start around the 2nd cycle is radiotherapy delivered to all known lesions. Preferably with SBRT /SRT/SRS but conventional radiotherapy may also be used. After the first three cycles of systemic treatment, the patients are assessed, and after four cycles, they are continuing maintenance therapy if indicated. The patients are followed with radiology every three months.


Clinical Trial Description

n/a


Study Design


Related Conditions & MeSH terms


NCT number NCT06141070
Study type Interventional
Source Vastra Gotaland Region
Contact Andreas Hallqvist
Phone +46313427954
Email andreas.hallqvist@vgregion.se
Status Not yet recruiting
Phase Phase 3
Start date December 1, 2023
Completion date December 1, 2027

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