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Disitamab Vedotin Combined Therapy for Locally Advanced or Metastatic NSCLC Patients With HER2 Alterations

Non Small Cell Lung Cancer Clinical Trial

Official title:
Disitamab Vedotin Combined Therapy for Locally Advanced or Metastatic NSCLC With HER2 Alterations, a Phase II Study

Clinical Trial Summary

Disitamab Vedotin combined therapy locally advanced or metastatic NSCLC Patients with HER2 Alterations.

Clinical Trial Description

This study will explore the treatment of locally advanced or metastatic non-small cell lung cancer with HER2 mutation, amplification, or HER2 mutation (mutation, amplification, protein over-expression) using Disitamab Vedotin（RC48） combined with Tislelizumab or third-generation EGFR-TKI Furmonertinib, in the aim of providing new treatment strategies for lung cancer patients with HER2 pathway activation. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT05847764
Study type Interventional
Source Sun Yat-sen University
Contact Li PI Zhang, MD
Phone 020-87343421
Email zhangli@sysucc.org.cn
Status Not yet recruiting
Phase Phase 2
Start date May 2023
Completion date May 2025
View Details
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