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Clinical Trial Summary

This is a Phase Ⅰ/Ⅱa, multi-center, open-label study, aiming to evaluate the safety, tolerability, pharmacokinetic (PK), and efficacy of BR790 in combination with anlotinib in adult participants with advanced NSCLC.


Clinical Trial Description

This study is a Phase Ⅰ/Ⅱa, multi-center, open-label study of BR790 in combination with anlotinib with a dose escalation part followed by a dose expansion part in adult subjects with advanced NSCLC. Participants will be treated until disease progression per RECIST v1.1, unacceptable toxicity, or other criteria for withdrawal are met, whichever occurs first. ;


Study Design


Related Conditions & MeSH terms


NCT number NCT05715398
Study type Interventional
Source Shanghai Gopherwood Biotech Co., Ltd.
Contact Baohui Han, professor
Phone 18930858216
Email 18930858216@163.com
Status Not yet recruiting
Phase Phase 1/Phase 2
Start date February 2023
Completion date December 2025

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