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NCT05205226 Clinical Trial

Local Radiotherapy for Residual Tumor Lesions During the First-line Treatment

Non Small Cell Lung Cancer Clinical Trial

Official title:
Efficacy and Safety of Local Radiotherapy for Residual Tumor Lesions During the First-line Treatment of Advanced Non-small Cell Lung Cancer: a Retrospective-real World Study

Clinical Trial Details — Status: Completed

Administrative data
NCT number NCT05205226
Other study ID # SPLENDOR
Secondary ID
Status Completed
Phase
First received
Last updated
Start date January 2, 2018
Est. completion date January 2, 2022

Study information
Verified date January 2018
Source Hunan Province Tumor Hospital
Contact n/a
Is FDA regulated No
Health authority
Study type Observational

Clinical Trial Summary

This study aimed to confirmed that local radiotherapy for residual lesions can significantly prolong the efficacy of chemotherapy combined with immunotherapy in the initial treatment of advanced non-small cell lung cancer.

Recruitment information / eligibility
Status Completed
Enrollment 636
Est. completion date January 2, 2022
Est. primary completion date June 5, 2021
Accepts healthy volunteers
Gender All
Age group 18 Years and older
Eligibility Inclusion Criteria: - =18,Advanced Non-small Cell Lung Cancer Confirmed by Histopathology Patients received platinum-based chemotherapy combined with immunotherapy Exclusion Criteria: - EGFR/ALK/ROS1 driver gene mutation - Chemotherapy only - Concurrent radio-chemotherapy - Surgery - Single-agent immunotherapy - No treatment information available

Study Design

Related Conditions & MeSH terms

Locations
Country Name City State
China Hunan Cancer Hospital Changsha Hunan

Sponsors (1)
Lead Sponsor Collaborator
Hunan Province Tumor Hospital

Country where clinical trial is conducted

China, 

Outcome
Type Measure Description Time frame Safety issue
Primary PFS Progression free survival time January 2018 to June 2021
Secondary RT radiotherapy control time January 2018 to June 2021
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