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NCT04324164 Clinical Trial

Survival Outcome of EGFR-TKI in Uncommon EGFR Mutant Advanced NSCLC

Non-small Cell Lung Cancer Clinical Trial

Official title:
Survival Outcome of EGFR-TKI in Uncommon EGFR Mutant Advanced Non-small Cell Lung Cancer in China

Clinical Trial Details — Status: Recruiting

Administrative data
NCT number NCT04324164
Other study ID # SONICS
Secondary ID
Status Recruiting
Phase
First received
Last updated
Start date March 24, 2020
Est. completion date December 24, 2025

Study information
Verified date December 2023
Source Hunan Province Tumor Hospital
Contact Yongchang Zhang, MD
Phone +8613873123436
Email zhangyongchang@csu.edu.cn
Is FDA regulated No
Health authority
Study type Observational

Clinical Trial Summary

This study aims to explore Survival Outcome of EGFR-TKI in Uncommon EGFR Mutant Advanced Non-small Cell Lung Cancer in China

Description:

inclusion criteria Uncommon EGFR Mutant Advanced Non-small Cell Lung Cancer EGFR G719X, exon 20 insert mutation without any anti-cancer treatment history

Recruitment information / eligibility
Status Recruiting
Enrollment 800
Est. completion date December 24, 2025
Est. primary completion date December 24, 2024
Accepts healthy volunteers
Gender All
Age group 18 Years and older
Eligibility Inclusion Criteria: - 18,Advanced Non-squamous Non-small Cell Lung Cancer Confirmed by Histopathology - Uncommon EGFR Mutant Advanced NSCLC Exclusion Criteria: - Patients with contraindication of chemotherapy - Pregnant or breast feeding women

Study Design

Related Conditions & MeSH terms

Locations
Country Name City State
China Yongchang Zhang Changsha Hunan

Sponsors (1)
Lead Sponsor Collaborator
Hunan Province Tumor Hospital

Country where clinical trial is conducted

China, 

Outcome
Type Measure Description Time frame Safety issue
Primary PFS Progression free survival may 2020- may 2021 (1 year)
Secondary OS Overall survival may 2020- may 2021 (1 year)
Secondary ORR To measure the patients's overall response rate may 2020- may 2021 (1 year)
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