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Study of Anlotinib Combined With Osimertinib as Second-line Treatment in Stage IIIb-IV NSCLC With Confirmed EGFRm and T790M — ALTN-03  

Non Small Cell Lung Cancer Clinical Trial

Official title:
A Multi-center, One-arm, Phase II Trial of Anlotinib Combined With Osimertinib as the Second-line Treatment in Stage IIIb-IV NSCLC With Confirmed EGFRm and T790M.

Clinical Trial Summary

Evaluate the efficacy and safety of Anlotinib combined with Icotinib as the second-line treatment in stage IIIb-IV NSCLC patients with sensitive EGFR and T790M mutations.

Clinical Trial Description

Anlotinib Hydrochloride is a kind of innovative medicines approved by State Food and Drug Administration（CFDA:2011L00661） which was developed by Jiangsu Chia-tai Tianqing Pharmaceutical Co., Ltd. Anlotinib is a kinase inhibitor of receptor tyrosine with multi-targets, especially for VEGFR1、VEGFR2、VEGFR3、FGFR1/2/3、PDGFRa/β and c-Kit. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT04029350
Study type Interventional
Source Tianjin Medical University Cancer Institute and Hospital
Contact
Status Enrolling by invitation
Phase Phase 2
Start date July 31, 2019
Completion date November 30, 2021
View Details
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