Non-Small Cell Lung Cancer Clinical Trial
Official title:
Randomized Study of PET/CT in Pre-Operative Staging of Lung Cancer
Patients with possible operable non-small cell lung cancer are randomised to conventional staging, or conventional staging and PET/CT. According to, patients with operable tumor will be referred to surgery, and the number of thoracotomies and futile thoracotomies wil be compared with the two groups in order to asses the possible benefit of PET/CT.
Status | Completed |
Enrollment | 189 |
Est. completion date | February 2008 |
Est. primary completion date | February 2007 |
Accepts healthy volunteers | No |
Gender | Both |
Age group | 18 Years to 80 Years |
Eligibility |
Inclusion Criteria: 1. Clinically operable NSCLC after CT 2. Fit for thoracotomy and lobectomy or pneumectomy after lung function tests 3. CT-scan of thorax, including liver and adrenals with no signs of distant metastases. 4. No medical condition contraindication surgery. 5. Age 18-80 6. No claustrophobia. 7. Negative pregnancy test. 8. No diabetes mellitus. 9. Signed informed consent. Exclusion Criteria: 1. Radiologically M1 disease. 2. Pregnancy 3. Known claustrophobia. 4. Estimated FEV1 < 30% of expected after surgery. 5. Diabetes mellitus. |
Time Perspective: Prospective
Country | Name | City | State |
---|---|---|---|
Denmark | PET & Cyclotron Unit, Rigshospitalet, | Copenhagen |
Lead Sponsor | Collaborator |
---|---|
Rigshospitalet, Denmark | Danish Cancer Society, Danish Centre for Health Technology Assessment |
Denmark,
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | Number of futile thoracotomies | Within 1 year | Yes | |
Secondary | Number of thoracotomies and survival | Within 1 year | Yes |
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