Non-Small Cell Lung Cancer Clinical Trial
Official title:
Correlation of Angiogenesis With 18F-FMT and 18F-FDG Uptake in Non-Small Cell Lung Cancer
Purpose: L-[3-18F]-α-methyltyrosine (18F-FMT) is an amino-acid tracer for PET. We have
conducted a clinicopathologic study to elucidate the correlation of angiogenesis with
18F-FMT and 18F-FDG uptake in the patients with non-small cell lung cancer (NSCLC).
Method: Thirty-seven NSCLC patients were enrolled in this study, and a pair of PET study
with 18F-FMT and 18F-FDG was performed. Uptake of PET tracers was evaluated with
standardized uptake value. VEGF, CD31, CD34, LAT1 and Ki-67 labeling index of the resected
tumors were analyzed by immunohistochemical staining, and correlated with the
clinicopathologic variables and the uptake of PET tracers.
n/a
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