PPIO-006 Primary Tumor Resection for IVa NSCLC

Non-small-cell Lung Cancer (NSCLC) Clinical Trial

Official title: Long-term Outcome of Primary Tumor Resection in Non-Small-Cell Lung Cancer Patients With Dry Pleural Dissemination: A Multi-center Study

Status Completed

Clinical Trial Summary

The goal of this mutli-center observational study is toinvestigate the impact of primary tumor resection (PTR) on the long-term survival of patients with non-small-cell lung cancer (NSCLC) and dry pleural dissemination (DPD). The main question it aims to answer is: whether primary tumor resection improve long-term survival of NSCLC patients with dry pleural dissemination.

Clinical Trial Description

Non-small-cell lung cancer (NSCLC) patients with dry pleural dissemination have poor survival rates and are generally contraindicated for surgery. Previous single-center retrospective studies have suggested that these patients may benefit from primary tumor resection (PTR). However, the evidence supporting PTR is still limited, especially in the era of targeted therapy. This study aimed to investigate the impact of PTR on the long-term survival of patients with NSCLC and DPD. ;

Related Conditions & MeSH terms

• Carcinoma, Non-Small-Cell Lung
• Lung Neoplasms
• Non-small-cell Lung Cancer (NSCLC)

• NCT number: NCT06232967
• Study type: Observational
• Source: Daping Hospital and the Research Institute of Surgery of the Third Military Medical University
• Status: Completed
• Start date: April 1, 2023
• Completion date: December 30, 2023