Non-small Cell Lung Cancer (NSCLC) Clinical Trial
Official title:
An Open-label, Randomized Phase 3 Efficacy Study of ASP8273 vs Erlotinib or Gefitinib in First-line Treatment of Patients With Stage IIIB/IV Non-small Cell Lung Cancer Tumors With EGFR Activating Mutations
The purpose of the study was to evaluate the progression free survival (PFS), based on
independent radiologic review (IRR), of ASP8273 compared to erlotinib or gefitinib in
patients with locally advanced, metastatic or unresectable stage IIIB/IV adenocarcinoma
non-small cell lung cancer (NSCLC) with epidermal growth factor receptor (EGFR) activating
mutations.
This study also assessed Overall survival (OS); Overall response rate (ORR) as assessed by
IRR; PFS as assessed by the investigator; Disease control rate (DCR) as assessed by IRR;
Duration of Response (DOR) by IRR; Safety of ASP8273; and Quality of Life (QOL) and
patient-reported outcome (PRO) parameters.
n/a
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