Hypofractionated Radiotherapy for Nonmelanoma Skin Cancer

Status Terminated

Clinical Trial Summary

Radiotherapy is a treatment considered standard for non melanoma skin cancer. This institution uses schemes of 4 to 6 weeks of treatment. The objective of the study is to perform radiation therapy in 1 to 2 weeks, depending on the size of the lesion.

Clinical Trial Description

Delineation of radiation field

- Gross tumor volume (GTV): disease clinically visible / palpable

- clinical target volume (CTV): equal to GTV

- planned treatment volume (PTV):

- tumors ≤ 2 cm in diameter, with 5-10 mm CTV margin

- tumors> 2-5 cm in diameter, with 15-20 mm CTV margin

- Marking the GTV and PTV pen back projection

- photograph of the treatment area

- protections of the normal structures with blocks of lead, if necessary

Technical

- Distance focus-skin Tube: 35 cm Locator: 30 and 40 cm

- Sizes Tube: 2, 3 and 4 cm in diameter Finder: 6x8 cm, 8x10 cm

- Energy:

80 kV 140 kv

- Filter 80 kV, 2 mm Al 140 kv, 0.5 mm Copper

- Current Draw: 20 mA

Dose

- tumors ≤ 2 cm in diameter: 5 fractions of 600 cGy, once a day, five times a week - TDF: 89

- tumors > 2-5 cm in diameter: 10 fractions of 400 cGy, once a day, five times a week - TDF: 96

Clinical revisions every 5 weekly sessions, or a weekly and at the end of treatment. ;

Study Design

Allocation: Non-Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Single Group Assignment, Masking: Open Label, Primary Purpose: Treatment

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT02080962
Study type	Interventional
Source	Barretos Cancer Hospital
Contact
Status	Terminated
Phase	Phase 2
Start date	January 2011
Completion date	February 2014

View Details

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