Non-Hodgkin's Lymphoma Clinical Trial
Official title:
A Phase 2 Multi-Center, Open-Label Study to Evaluate the Efficacy and Safety of Patient-Specific Immunotherapy, Recombinant Idiotype Conjugated to KLH (Id-KLH) and Administered With GM-CSF, in Patients With Follicular Non-Hodgkin's Lymphoma (fNHL) Following Primary Treatment With Rituximab and Chemotherapy (R-Chemo)
The treatment being investigated is a patient- and tumor-specific therapy known as a
personalized active immunotherapy. Personalized active immunotherapy is an attempt to use a
person's own immune system to combat disease. Sargramostim (a.k.a. GM-CSF) is given together
with the personalized active immunotherapy because it may increase the immune system's
response and, therefore, aid in the effect of the personalized active immunotherapy.
This approach has previously been studied in patients with follicular Non-Hodgkin's lymphoma
and other B-cell malignancies. Encouraging efficacy results and a favorable safety profile
have been seen to date in these studies.
n/a
Intervention Model: Single Group Assignment, Masking: Open Label
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|---|---|---|---|
| Active, not recruiting |
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