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Clinical Trial Summary

The trial is a single arm, single-center, non-randomized phase I clinical trial which is designed to evaluate the safety and efficacy of C-CAR039 in treatment of relapsed or refractory NHL patients


Clinical Trial Description

This study plans to enroll 25 patients to assess the safety and efficacy of C-CAR039. Subjects who meet the eligibility criteria will receive a single dose of C-CAR039 injection. The study will include the following sequential phases: Screening, Apheresis and C-CAR039 manufacturing, Bridging (if needed), Baseline, lymphodepletion, C-CAR039 infusion, and Follow-up Visit. ;


Study Design


Related Conditions & MeSH terms


NCT number NCT04317885
Study type Interventional
Source Shanghai Tongji Hospital, Tongji University School of Medicine
Contact
Status Active, not recruiting
Phase Phase 1
Start date November 5, 2019
Completion date December 30, 2023

See also
  Status Clinical Trial Phase
Active, not recruiting NCT04696432 - A Study of C-CAR039 Treatment in Subjects With r/r NHL SubjectsNon-Hodgkin's Lymphoma Phase 1
Terminated NCT02361346 - Safety, PD & Efficacy of MT-3724 for the Treatment of Patients With Relapsed or Refractory DLBCL Phase 1/Phase 2
Active, not recruiting NCT04693676 - A Study of C-CAR039 Treatment in Subjects With r/r NHL Subjects Non-Hodgkin's Lymphoma Phase 1
Recruiting NCT04655677 - A Study of EXP039 Treatment in Subjects With r/r NHL Subjects Phase 1
Suspended NCT04148742 - Assessing an Oral Bruton Tyrosine Kinase Inhibitor, DZD9008 in Patients Who Have Non-Hodgkin B-cell Lymphoma (WU-KONG3) Phase 1/Phase 2
Active, not recruiting NCT03000192 - HORIZONS: Understanding the Impact of Cancer Diagnosis and Treatment on Everyday Life
No longer available NCT02715843 - Extended Treatment Access Study of MT-3724 for Subjects With Relapsed Non-Hodgkin's B-Cell Lymphoma