Open-label Study of Surufatinib in Japanese Patients

Status Active, not recruiting

Clinical Trial Summary

This is a phase 1/2, open-label, multi-centre study of surufatinib in patients with unresectable, locally advanced, or recurrent nonhematologic malignancies who do not respond or are intolerant to standard of care.

Clinical Trial Description

The purpose of this study is to evaluate the tolerability and efficacy of surufatinib in Japanese patients. The study will be conducted in 2 parts: - Part 1 - evaluation of tolerability and safety of surufatinib and confirmation of the recommended clinical dose in Japanese patients with nonhematologic malignancies - Part 2 - evaluation of antitumor activity and confirmation of tolerability of surufatinib in Japanese patients with NETs All patients will be treated with oral surufatinib 300 mg QD in treatment cycles of 28 days starting on Cycle 1 Day 1. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT05077384
Study type	Interventional
Source	Hutchmed
Contact
Status	Active, not recruiting
Phase	Phase 1/Phase 2
Start date	September 2, 2021
Completion date	December 2024

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