Nocturnal Leg Cramps Clinical Trial
Official title:
Prevalence, Main Features and Treatment of Nocturnal Leg Cramps in Geneva: A Primary Care Prospective Observational Study
Background :
Nocturnal leg cramps (NLC) are defined as painful involuntary contractions of the lower limbs
occurring during prolonged periods of rest, typically during the night. They may cause severe
pain and sleep disturbance, and are particularly common among older adults, though they can
occur in all decades of life. They are frequently unreported to physicians. To the
investigators' knowledge, no epidemiological studies have been conducted in Switzerland, but
in a general population survey carried out in the UK (n=233), the overall prevalence of NLC
was 37% and the disorder was more prevalent in older subjects (>80 years old: 54%). Of those
who experienced NLC, 40% had cramps three or more times per week and 6% nightly. Another
study performed in older US veterans (n=515) showed that 56% suffered from NLC.
The precise cause of these cramps is unclear. Most NLC occurring in adults appear to be
idiopathic, but potential contributing factors include low levels of certain minerals,
extracellular fluid volume depletion and prolonged sitting or inappropriate leg position
during sedentary activity.
Research question :
What are the prevalence and the main features of NLC in patients consulting primary care
physicians (PCPs) in Geneva, and how do PCPs treat this affection?
Primary objective :
To compute the prevalence of NLC in patients consulting PCPs in Geneva, explore its main
features (number, duration, severity and sleep disturbance) and assess how PCPs treat this
affection.
Study design :
Prospective observational study using questionnaire and daily log completed by patients.
n/a
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