No-Reflow Phenomenon Clinical Trial
Official title:
Metabolic Profile as a Predictor of No-reflow in Diabetic Patients Treated With Primary Percutaneous Coronary Intervention (PCI)
1- to find metabolic factors that correlate with the development of no reflow phenomenon that may help prevent its occurrence .
Status | Not yet recruiting |
Enrollment | 120 |
Est. completion date | May 2022 |
Est. primary completion date | May 1, 2022 |
Accepts healthy volunteers | Accepts Healthy Volunteers |
Gender | All |
Age group | N/A and older |
Eligibility | Inclusion Criteria: - diabetic patients with STEMI treated with primary PCI Exclusion Criteria: non diabetic . with selected PCI - (1) a history of an unprotected left main artery with severe liver and kidney diseases or coronary artery bypass grafting . (2) patients who had valvular disease or cardiomyopathy . (3) severe dissection, thromboembolism in other parts, or vasospasm; and known malignancy . (4) patients with contraindications for anticoagulant therapy, such as active visceral hemorrhage, hemorrhagic stroke, or ischemic stroke within half a year (including transient ischemic attack), or aortic dissection, or patients with hematological diseases complicated with coagulation disorders . |
Country | Name | City | State |
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n/a |
Lead Sponsor | Collaborator |
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Assiut University |
Bernstein JM, Lee J, Conboy K, Ellis E, Li P. The role of IgE mediated hypersensitivity in recurrent otitis media with effusion. Am J Otol. 1983 Jul;5(1):66-9. — View Citation
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | measure serum random blood sugar | to detect the correlation between the diabetus mellitus (serum random blood sugar) and no-reflow phenomenon and analysis of this metabolic factors in patient withSTEMI who will undergo primaru PCI and show its effects on no-reflow phenomenon that may help prevent its occurrence . | baseline | |
Secondary | measure the serum uric acid | to detect the correlation between the serum uric acid , lipid profile and no-reflow phenomenon and show other metabolic factors effects on no-reflow to avoid its occurance | baseline | |
Secondary | measure the lipid profile | to detect the correlation between lipid profile and no-reflow phenomenon | baseline |
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