Matcha Green Tea Effects at Rest and During Moderate-intensity Exercise in Females

No Condition Clinical Trial

Official title:

Effects of Matcha Green Tea on Heart Rate Variability, Substrate Oxidation and Cardiovascular Response at Rest and During Moderate-intensity Exercise in Females

Clinical Trial Details — Status: Recruiting

Administrative data

• NCT number: NCT05882942
• Other study ID #: 22231905455
• Status: Recruiting
• Phase: N/A
• Start date: March 3, 2023
• Est. completion date: August 15, 2023

Study information

• Verified date: May 2023
• Source: University of Chichester
• Contact: Mark E Willems, PhD
• Phone: +4401243816468
• Email: m.willems[@]chi.ac.uk
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

Intake of the green tea catechin epigallocatechin (EGCG) increased fat oxidation during walking. It is also known to reduce blood pressure and improve body composition. This research will expand the insight on the effects by Matcha green tea supplementation and address the effects on heart rate variability, substrate oxidation at rest, and cardiovascular responses at rest in addition to metabolic and physiologic responses for a 1-hr walk in healthy females.

Description:

Intake of the catechin epigallocatechin (EGCG) increased fat oxidation during walking. It is also known to reduce blood pressure and improve body composition. EGCG is the most abundant and potent bioactive compound (50-80% of the total catechin content) found in Matcha green tea (MGT) and is usually consumed as a drink or in a capsulated from unfermented tea leaves. MGT polyphenols have antioxidant and anti-inflammatory properties, providing numerous health benefits, such as the reduced risk of type 2 diabetes and obesity. MGT supplementation (3g over a 24hr period) has been shown to enhance fat oxidation during 30-min brisk walking as well as lower respiratory exchange ratio in females. Understanding the effectiveness of the bioactive compounds found in natural food sources in improving human health is key to informing the general population and the public health policies preceding them; the daily consumption of drinks and food naturally high in EGCG content could be recommended as an essential part of a healthy lifestyle. This research will expand the insight on Matcha green tea supplementation address the effect on heart rate variability, substrate oxidation at rest, and cardiovascular responses at rest in addition to metabolic and physiologic responses for a 1-hr walk in healthy females.

Recruitment information / eligibility

• Status: Recruiting
• Enrollment: 14
• Est. completion date: August 15, 2023
• Est. primary completion date: July 26, 2023
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: Female
• Age group: 18 Years to 30 Years

Eligibility

Inclusion Criteria:

• healthy
• non-smokers
• not taking any supplements
• no known allergy to green tea

Exclusion Criteria:

• smokers
• known high blood pressure
• on medication

Related Conditions & MeSH terms

• No Condition

Intervention

Dietary Supplement:
• Matcha green tea
This is the condition with the Matcha green tea
• Placebo
This is the condition with the placebo

Locations

Country	Name	City	State
United Kingdom	Mark Willems	Chichester	West Sussex
United Kingdom	University of Chichester	Chichester

Sponsors (1)

Lead Sponsor	Collaborator
University of Chichester

Country where clinical trial is conducted

United Kingdom, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Heart rate variability	Measurement of root mean square of standard deviation of RR intervals	Three weeks
Primary	Carbohydrate oxidation	Measurement of carbohydrate oxidation in grams/minute	Three weeks
Primary	Fat oxidation	Measurement of fat oxidation in grams/minute	Three weeks
Primary	Cardiac output	Measurement of cardiac output in liters per minute	Three weeks
Primary	Stroke volume	Measurement of stroke volume in milliliters	Three weeks
Primary	Total peripheral resistance	Measurement of total peripheral resistance in (mmHg x min) / mL	Three weeks