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Clinical Trial Summary

To observe the safety, tolerability and clinical effects of PD-1 Antibody, Chidamide, Lenalidomide and Etoposide in Relapsed or Refractory NK/T cell Lymphoma.


Clinical Trial Description

This is a prospective, open-label, one-arm, multicenter clinical trial, aimed to evaluate the safety, tolerability, and efficacy of PD-1 Antibody, Chidamide, Lenalidomide and Etoposide in Relapsed or Refractory NK/T cell Lymphoma. A total of 50 patients are planned to be enrolled into the study. The primary end points are objective responder rate (ORR) and progression free survival(PFS) and the secondary end points include overall survival(OS) , and adverse events. ;


Study Design


Related Conditions & MeSH terms


NCT number NCT04038411
Study type Interventional
Source Zhengzhou University
Contact Mingzhi D Zhang
Phone +8613838565629
Email Mingzhi_zhang@126.com
Status Recruiting
Phase Phase 4
Start date April 1, 2019
Completion date April 1, 2022

See also
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Not yet recruiting NCT05208853 - An Exploratory Clinical Study Evaluating the Safety and Efficacy of Anti CD30 CAR T Cells in Patients With CD30+ Relapsed/Refractory Lymphoma Early Phase 1
Withdrawn NCT04230330 - Nivolumab in Combination With GDP/ L-asparaginase in NK/ T-cell Lymphoma Phase 1
Recruiting NCT04004637 - CD7 CAR-T Cells for Patients With R/R CD7+ NK/T Cell Lymphoma,T-lymphoblastic Lymphoma and Acute Lymphocytic Leukemia Phase 1
Completed NCT01660568 - Gemcitabine in NK/T Cell Lymphoma N/A