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Clinical Trial Summary

Dysfunction of natural koller cells (NK cells) is an important factor in the development of endometriosis. NK cell therapy was applied to treat severe endometriosis, which is an exploration of the pathogenesis of this refractory disease.


Clinical Trial Description

Endometriosis (EMs) is one of the common and frequently occurring diseases in women of childbearing age, which seriously affects the health and quality of life of the vast majority of women. The pathogenesis of endometriosis is unknown until now, and the recurrence rate of existing treatment methods is high. It is more and more necessary to introduce new therapeutic methods and strategies in view of the mechanism associated with the reduction of natural killer cell (NK) cytotoxicity. In this study, routine therapy combined with NK cell therapy was used in the treatment of severe endometriosis. The clinical data were collected to confirm the efficacy and safety of NK cell therapy. It is expected to provide a new way of thinking and method for the clinical treatment of EMs. ;


Study Design


Related Conditions & MeSH terms


NCT number NCT03948828
Study type Interventional
Source Shenzhen People's Hospital
Contact Lili Ren, Ph.D
Phone +86-755-22942466
Email ren.lili@szhospital.com
Status Not yet recruiting
Phase Phase 1
Start date June 1, 2019
Completion date December 31, 2022

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