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N-Acetylcysteine and Smoking Reduction

Nicotine Dependence Clinical Trial

Official title:
A Randomized Controlled Trial of Oral N-acetylcysteine for Smoking Reduction: a Pilot Study

Clinical Trial Summary

N-acetylcysteine is an inexpensive agent with a benign side effect profile with preliminary studies in humans suggesting efficacy for the treatment of cocaine dependence. N-acetylcysteine has been used in clinical medicine for nearly three decades to treat chronic lung conditions, acetaminophen overdose, and experimentally to treat cocaine dependence. It is generally safe and well tolerated. The present pilot study seeks to explore safety and tolerability, ad lib smoking, visual cue reactivity, and smoking reduction rates in a group of nontreatment seeking, nicotine dependence smokers who are willing to undergo a brief trial with oral N-acetylcysteine 1200 mg twice daily.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT00751257
Study type Interventional
Source Medical University of South Carolina
Contact
Status Completed
Phase Phase 2
Start date December 2006
Completion date October 2007
View Details
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