Brain Reaction to Treatment of Nicotine Dependence

Status Completed

Clinical Trial Summary

The purpose of the study was to determine how the treatments for cigarette craving work.

Hypothesis: During exposure to cigarette-related cues, heavy smokers will have greater reductions in regional brain activation from before to after both forms of active treatments than from before to after placebo.

Clinical Trial Description

PET and fMRI scanning were used to examine brain activity and activation in cigarette smokers in response to cigarette-related cues. ;

Study Design

Intervention Model: Parallel Assignment, Masking: Open Label, Primary Purpose: Diagnostic

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT00108173
Study type	Interventional
Source	VA Office of Research and Development
Contact
Status	Completed
Phase	Phase 1
Start date	October 2002
Completion date	June 2011

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See also
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